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Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial

RecruitingNAAges 18 Years - 55 YearsAllUniversidad Autonoma de Nuevo Leon
NCT07497555 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate whether daily supplementation with cold-pressed pecan nut oil can reduce inflammation in adults with overweight. The main questions it aims to answer are: Does pecan nut oil supplementation reduce inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α)? Does pecan nut oil supplementation improve biochemical parameters such as fasting blood glucose and lipid profile? Researchers will compare an experimental group receiving pecan nut oil to a control group with no intervention to determine its effect on inflammation and metabolic parameters. Participants will: Consume 30 g/day of cold-pressed pecan nut oil under fasting conditions for 8 weeks (experimental group) Maintain their usual diet and physical activity throughout the study Attend two evaluation visits (baseline and D

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 to 65 years * Body mass index (BMI) ≥25 and \<30 kg/m² (overweight) * Willingness to participate and provide written informed consent * Ability to comply with study procedures and attend scheduled visits * Stable dietary habits and physical activity levels during the study period Exclusion Criteria: * Diagnosis of chronic diseases such as diabetes mellitus, cardiovascular disease, liver disease, renal disease, or autoimmune disorders * Use of anti-inflammatory medications, lipid-lowering drugs, or dietary supplements within the last 3 months * Smoking or excessive alcohol consumption * Pregnancy or lactation * Known allergy or intolerance to nuts or nut-derived products * Participation in another clinical trial within the last 3 months * Any condition that, in the investigator's opinion, may interfere with study participation or outcomes
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What it tests

  • Pecan nut oil supplementation
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Where

1 site
Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León
Monterrey, Mexico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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