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Effect of Morus Nigra Mouthwash on Gingivitis Treatment

RecruitingNAAges 18 Years - 65 YearsAllInonu University
NCT07499596 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of generalized gingivitis (Gingival Index \> 1). * Presence of at least 20 natural teeth. * Systemically healthy individuals. * Ability to provide informed consent. Exclusion Criteria: * Smoking or use of tobacco products. * Presence of periodontitis (no clinical attachment loss). * Use of antibiotics or anti-inflammatory drugs in the last 6 months. * Pregnancy or lactation. * History of allergy to Morus nigra or mouthwash components. * Systemic diseases (Diabetes, cardiovascular diseases, etc.).
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What it tests

  • Scaling and Root Planing
  • Morus Nigra Mouthwash
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Where

1 site
Inonu University Faculty of Dentistry
Battalgazi, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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