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Exploratory Clinical Evaluation of Personalized Functional Profiling in GI Tumors: Predicting Drug Response in CRC and PDAC

Recruitingn/aAges 18 Years - anyAllLuxembourg Institute of Health
NCT07500259 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The ColoPan study evaluates the scientific validity, reproducibility, and predictive performance of the Personalised Functional Profiling (PFP) platform in colorectal cancer and pancreatic ductal adenocarcinoma patients. It combines genomic sequencing with in vitro functional drug testing using patient-derived spheroids/organoids.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Signed informed consent form * ≥ 18 years of age * Willing and able to comply with the protocol for the duration of the study, including data and sample collection * Patient scheduled for surgery or biopsy (primary tumour or metastasis) PDAC Exclusion Criteria: * Female patient, pregnant, planning a pregnancy or breastfeeding. * Known active Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), or Hepatitis C Virus (HCV) infection. * Patient unable to understand and provide informed consent and has no family member representing him/her. * Patients with any other life-threatening illness, significant organ dysfunction or any clinically relevant conditions that, according to the hospital physician, could compromise the patient's safety.
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What it tests

  • Personalized Functional Profiling
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Where

1 site
Hôpitaux Robert Schmuan
Luxembourg, Luxembourg
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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