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โ† Trials
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Muscle Health Measurements Using Electrical Impedance Myography

Recruitingn/aAges 18 Years - 89 YearsAllBeth Israel Deaconess Medical Center
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In plain words

What the trial is, and whether it could suit you

This study is being done to further develop a device, the mScan, to measure muscle health as compared to measurements of muscle health using MRI (magnetic resonance imaging). This device is held against the skin and uses Electrical Impedance Myography (EIM). EIM uses a very small, noninvasive (e.g. no needles), brief (about 6 seconds), and painless electrical current to measure the muscle. The investigators will look at how the mScan predicts the muscle measurements seen on MRI in people with and without muscle disease. The investigators hope that this can be used in the future as a quick, convenient and less time-consuming way than MRI to assess muscle health. This could be used to measure how well treatments for different muscle disorders are working over a period of time.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Ages 18-89 * Evidence of a primary myopathic condition as determined by detailed chart review, including results of genetic testing, serological data, or previous muscle biopsy Exclusion Criteria: * Inability to lie flat or history of claustrophobia * \>1+ lower extremity edema * Presence of multiple other pathologies affecting lower extremity muscles to be studied * Pregnancy * Contraindications for MRI scanning - e.g. MRI incompatible pacemaker, deep brain stimulator, or lower extremity hardware * Contraindications to undergo DXA Scan * Any studies/scans with a radioisotope within the past 15 days * Any imaging with radiographic contrast in the past 7 days * Weight greater than 450 lbs * Calcium supplements or antacids containing calcium in the past 24 hours * Severe obesity with BMI \> 35 kg/m2, given difficulties fitting in MRI scanner and impact of severe obesity on EIM data * Chronic skin conditions with ulcerations which would interfere with EIM electrode contact or be uncomfortable for the participant
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What it tests

  • Electrical Impedance Myography
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Where

1 site
Beth Israel Deaconess Medical Center
Boston, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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