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Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy

RecruitingNAAges 18 Years - 65 YearsAllFayoum University Hospital
NCT07507799 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST). In such a bilaterally administered regional technique, evaluating the efficacy of a reduced-volume approach is warranted to maximize patient safety.

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📋 Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I or II. * Scheduled for elective laparoscopic cholecystectomy under general anesthesia. Exclusion Criteria: * • Patient refusal to participate. * Obese patients with a body mass index of more than 35 kg/m2. * Known cognitive impairment or use of psychiatric drugs * Known allergy to local anesthetics * Infection at the needle insertion site. * Coagulopathy, or bleeding disorders. * Pregnancy * History of chronic pain or chronic opioid use. * Previous major upper abdominal surgery (which alters the fascial planes and anatomy). Criteria for Withdrawal from Study Analysis (Drop-outs): * Conversion to open cholecystectomy during surgery. * Failed EXORA block
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What it tests

  • EXORA block 15
  • EXORA block 25
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Where

1 site
Fayoum University hospital
El Fayoum Qesm, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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