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The Hypotension Prediction Index Versus Standard Advanced Haemodynamic Monitoring in Patients Undergoing Major Aortic Surgery

RecruitingNAAges 18 Years - anyAllPoznan University of Medical Sciences
NCT07510451 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The standard procedure during general anesthesia is to monitor vital functions, including cardiovascular functions such as cardiac electrical activity, using continuous ECG recording, blood pressure measurement with a sphygmomanometer, heart rate measurement, and tissue oxygenation measurement with a pulse oximeter. These are non-invasive methods, which are often insufficient in the case of extensive procedures within the abdominal aorta. In such cases, the anesthesiologist additionally use direct blood pressure measurements and central venous pressure measurements. To perform these measurements, it is necessary to insert a cannula into an artery (usually the radial artery) and a catheter into the central veins (through the internal jugular or subclavian vein). Vascular cannulation is an invasive method and may be associated with complications such as vascular thrombosis, infection at th

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 years 2. American Society of Anesthesiologists (ASA) physical status classification III or IV 3. Scheduled for elective major abdominal aortic surgery (open or endovascular repair) with an expected surgical duration exceeding 2 hours 4. Able to provide written informed consent Exclusion Criteria: 1. Emergency or urgent surgery 2. Pregnancy or breastfeeding or positive/uncertain pregnancy test 3. Haemodynamically significant valvular heart disease: * Severe aortic stenosis (aortic valve area \< 1.5 cm\^2) * Moderate to severe aortic regurgitation * Moderate to severe mitral regurgitation * Moderate to severe mitral stenosis 4. Severe heart failure with left ventricular ejection fraction \< 35% 5. Permanent atrial fibrillation (reduces accuracy of pulse contour analysis) 6. Inability to provide informed consent 7. Participation in another interventional trial that may influence haemodynamic management or study outcomes
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What it tests

  • HPI guided heamodynamic monitoring
  • Standard Heamodynamic Managament according to APCO Monitoring
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Where

1 site
Department of Anesthesiology and Intensive Therapy
Poznan, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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