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โ† Trials
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Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM)

Recruitingn/aAges 18 Years - anyAllKnappschaft Kliniken GmbH
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn whether heterotopic gastric mucosa (HGM) in the upper esophagus is associated with swallowing difficulties (dysphagia) in adults undergoing a medically indicated gastroscopy. The main questions it aims to answer are: * Is the presence of HGM associated with dysphagia? * Is the presence of HGM associated with dyspepsia and reduced health-related quality of life? Among participants reporting dysphagia, what is the distribution of oropharyngeal versus esophageal dysphagia, and is this related to the presence of HGM? If there is a comparison group: Researchers will compare participants with endoscopically confirmed HGM to participants without HGM to determine whether dysphagia, dyspepsia symptoms, and quality-of-life measures differ between groups. Participants will: Complete pseudonymised questionnaires about dysphagia, dyspepsia symptoms,

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Planned upper gastrointestinal endoscopy (gastroscopy) for clinical reasons (any indication) * Age โ‰ฅ 18 years * Written informed consent * Ability to complete the study questionnaires prior to endoscopy Exclusion Criteria: * Previously known heterotopic gastric mucosa (HGM) * Previously diagnosed dysphagia with prior therapeutic intervention (including pre-established diet modification, partial oral/enteral nutrition, steroid therapy, botulinum toxin injection, etc.) * Mechanical ventilation * Presence of a tracheostomy * Inadequate endoscopic assessability of the proximal esophagus, including: * General condition insufficient for careful endoscopic inspection (investigator's judgement) * Increased risk of aspiration * Inadequate visibility during the procedure (e.g., bleeding, food residue) * Complications preventing careful inspection of the proximal esophagus * History of surgery involving the pharynx or esophagus * Relevant severe neurological disorder (e.g., ALS, stroke) * Severe dementia * Severe depressive disorder * Lack of cooperation / inability to comply with study procedures * Planned PEG placement * Emergency endoscopy
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What it tests

  • Not listed
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Where

1 site
Knappschaftskrankenhaus Bottrop
Bottrop, Germany
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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