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Effect of Rebound Pain on Chronic Postsurgical Pain After Total Knee Arthroplasty

Recruitingn/aAges 18 Years - anyAllKonya City Hospital
NCT07511985 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational study aims to evaluate whether rebound pain after peripheral nerve block is associated with the development of chronic postsurgical pain following elective total knee arthroplasty. Adult patients undergoing unilateral total knee arthroplasty under spinal anesthesia and receiving a peripheral nerve block as part of routine multimodal analgesia will be included. No additional intervention, drug administration, or biological sampling will be performed beyond standard clinical care. Rebound pain will be assessed during the early postoperative period using pain diaries, numeric rating scale pain scores, and analgesic consumption records. Chronic postsurgical pain and related outcomes will be evaluated at postoperative 3 and 6 months using validated instruments assessing pain severity, neuropathic pain features, psychological status, functional outcomes, and hea

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older * ASA physical status I to III * Scheduled for unilateral elective total knee arthroplasty * Planned to undergo spinal anesthesia * Planned to receive a peripheral nerve block as part of routine multimodal analgesia * Able to provide informed consent and complete study assessments Exclusion Criteria: * Chronic opioid use (60 mg oral morphine equivalent per day or more, or use for 3 months or longer) * Significant neuropathy or radiculopathy * Bilateral or two-stage total knee arthroplasty during the same hospitalization * Contralateral total knee arthroplasty within the previous 6 months * Severe cognitive impairment or major psychiatric disorder * Chronic analgesic dependence
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What it tests

  • Not listed
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Where

1 site
Mahmut TUTAR
Konya, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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