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Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes

Recruitingn/aAges 18 Years - 74 YearsAllWest Kazakhstan Marat Ospanov Medical University
NCT07512934 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to better understand how the pancreas works in adults with type 2 diabetes. The study focuses on both hormone production (endocrine function) and digestive function (exocrine function) of the pancreas. The main questions it aims to answer are: * Can problems with the pancreas help identify a different type of diabetes called pancreatogenic diabetes? * How are blood markers and pancreas structure related to pancreatic function? Participants will: * Have blood tests to measure glucose, insulin, and other markers * Provide a stool sample to assess digestive function * Undergo an ultrasound examination of the pancreas * Answer questions about digestive symptoms The study will take place during a single visit in outpatient clinics.

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📋 Eligibility rules (as published)
Inclusion Criteria: * • adult patients of Kazakh nationality aged 18 to 74 years * diagnosis of T2DM established according to ADA criteria and documented in medical records * disease duration ≤5 years * absence of ketoacidosis episodes within the last 6 months Exclusion Criteria: * positive anti-glutamic acid decarboxylase antibodies (anti-GAD65); * acute or chronic infections affecting metabolic status within the previous 4 weeks; * any history of malignant neoplasms; * pregnancy or lactation; * previously diagnosed type 1 diabetes mellitus or other specific types of diabetes; * severe decompensated chronic diseases; * conditions associated with systemic fibrosis (e.g., liver cirrhosis or autoimmune diseases); * refusal to participate.
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What it tests

  • Not listed
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Where

1 site
Outpatient clinics of Aktobe region, West Kazakhstan Marat Ospanov Medical University
Aktobe, Kazakhstan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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