Investigation of the Effectiveness of Exercise and Anti-Fibrotic Approaches in Frozen Shoulder

Inclusion Criteria: * Adults aged 18 years or older diagnosed with frozen shoulder (adhesive capsulitis) * Having less than 50% of range of motion (ROM) in at least one of the following shoulder movements compared to the unaffected side: external rotation, abduction, flexion, or internal rotation * Having more than 25% loss of ROM in at least two movement planes compared to the unaffected shoulder * Patients in stage II or III of frozen shoulder Exclusion Criteria: * Women who are pregnant, breastfeeding, or planning pregnancy during the study * Patients in stage I of frozen shoulder * Patients diagnosed with inflammatory or other types of arthritis due to autoimmune diseases affecting the shoulder * Patients with rotator cuff pathology and/or glenohumeral arthritis * Patients with a history of prior shoulder infection * Patients with hypotension * Patients who have undergone previous upper extremity surgery or plan to undergo upper extremity surgery during the study period * Patients with allergy to losartan or its active/inactive components * Patients taking medications known to have adverse interactions with losartan * Patients who, in the investigator's opinion, have any medical condition, laboratory abnormality, or history that could pose risk, contraindicate participation, affect the conduct, objectives, or evaluation of the study, or prevent full participation in the study