🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults

RecruitingNAAges 60 Years - 90 YearsAllThe Hong Kong Polytechnic University
NCT07513701 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty. Investigator contend that enhanced physical reserve will enable preservation of cognitive and physical function. The main questions aims to answer are: (1) Compared with usual care (i.e., CON), will 3-month aerobic and resistance training (ATRT) improve physical reserve in older adults with physical frailty? (2) Compared with CON, will ATRT lead to changes in the neural network organization? (3) Will improved physical reserve lead to better maintenance of cognitive and physical functioning in spite of presence of white matter hyperintensities (WMH)?

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. are community-dwelling (i.e., not residing in a nursing home or extended care unit) ; 2. scored \< 9/12 on the SPPB; 3. scored \>18/30 on the MoCA; 4. are able to walk independently; use of walking aid is acceptable; 5. are able to safely engage in exercise as indicated by the Physical Activity Readiness Questionnaire Plus33 and confirmed by their physician; 6. have internet at home; and 7. are able to provide written informed consent. Exclusion Criteria: 1. diagnosed with dementia or stroke; 2. self-report engaging in strength and balance training exercises \> two-times-per-week in the 3 months prior to screening; 3. unable to understand, speak, and read Cantonese/Chinese/English proficiently; and 4. contraindications for MRI such as MRI-incompatible implants.
💊

What it tests

  • Aerobic and resistance training
  • Usual Care
📍

Where

1 site
The Hong Kong Polytechnic University, Department of Rehabilitation Sciences
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy