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Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery

RecruitingNAAges 18 Years - anyAllShanghai Chest Hospital
NCT07515027 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients undergoing thoracoscopic lung cancer surgery. The primary outcome is the incidence of PONV within 24 hours after surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years; * American Society of Anesthesiologists (ASA) physical status I-III; * Body mass index (BMI) 18-30 kg/m²; * Scheduled for elective video-assisted thoracoscopic surgery (VATS) lobectomy, segmentectomy, or wedge resection; * Expected to receive postoperative opioid analgesia, with an Apfel risk score ≥ 3; * Normal pulmonary function, without severe cardiovascular, hepatic, or renal abnormalities; * No infection around the acupuncture sites; * Voluntary written informed consent provided by the subject. Exclusion Criteria: * Severe systemic diseases, such as cardiovascular, hepatic, or renal abnormalities, or poor pulmonary function; * Subjects with cognitive dysfunction or psychological disorders; * History of previous esophageal or gastric surgery; * Hypersensitivity to acupuncture or any study medications; * Severe infection or history of surgery around the acupuncture sites; * Pregnant or lactating women; * Long-term opioid use; * Conversion to open surgery; * Acupuncture treatment received within 1 month prior to enrollment.
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What it tests

  • Prophylactic administration of dolasetron
  • Electroacupuncture
  • Sham electroacupuncture
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Where

1 site
Shanghai Chest Hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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