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Intramuscular Injection of Mashed Parathyroid Tissue Into a Forearm During Thyroid Surgery to Prevent Permanent Postoperative Parathyroid Insufficiency (IMIPAT Study)

RecruitingNAAges 18 Years - anyAllMedical University of Vienna
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In plain words

What the trial is, and whether it could suit you

Parathyroid insufficiency is a common complication in thyroid surgery and occurs in 6.6 to 24%. Up to 4.4% suffer from permanent hypoparathyroidism requiring life-time substitution of calcium and vitamin D in order to maintain a normal calcium homeostasis. To prevent permanent postoperative parathyroid insufficiency after thyroidectomy, devascularized parathyroid glands are re-implanted intramuscularly by standard. To achieve graft function, meticulous preparation and division of parathyroid tissue is necessary as a prerequisite for tissue nutrition by diffusion until a recapillarization of the parathyroid fragments sets in. There are persistent controversies about the optimal technique for the autotransplantation. The injection of mashed parathyroid tissue into a muscle appears to be a fast, secure and easy tech-nique to provide a sufficient parathyroid hormone (PTH) production in cases

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * signed informed consent * parathyroid autotransplantation in forearm performed during thyroid surgery * 18 years of age and above Exclusion Criteria: * under 18 years of age * informed consent not signed * hyperparathyroidism * no parathyroid autotransplantation performed
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What it tests

  • Intramuscular injection of mashed parathyroid tissue into the brachioradial muscle during thyroid surgery
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Where

2 sites
Wiener Gesundheitsverbund, Klinik Landstrasse
Vienna, Austria
Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna
Vienna, Austria
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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