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โ† Trials
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Exercises for Rehabilitation of COgnition and Lifestyle Enhancement in Patients With Mild Cognitive Impairment

RecruitingNAAges 50 Years - anyAllCasa di Cura IGEA
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In plain words

What the trial is, and whether it could suit you

Mild Cognitive Impairment (MCI) is a clinical condition with a heterogeneous etiology and clinical course characterized by objective cognitive deficits not severe enough to cause clear functional limitations or to warrant a diagnosis of dementia. Since MCI represents a risk factor for progression to various forms of dementia, timely preventive intervention is essential, although outpatient cognitive rehabilitation for this population is still limited by issues related to service accessibility. This study aims to investigate the effectiveness of a multimodal group cognitive rehabilitation intevention designed to be accessible for patients with MCI and sustainable in clinical practice. The primary objective of the study is to evaluate the effects of the intervention on cognitive, behavioural, and functional profile of patients with MCI, compared with an active control group. Outcome meas

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of MCI according to the diagnostic criteria of Petersen (2004) and Winblad et al. (2004) and, if applicable (i.e., MCI due to AD), according to those of Albert and colleagues (2011). * Self-reported basic skills in using technological devices, or access to a close person able to provide assistance. * Willingness of the patient to report, during the study period, any changes in the dosage of psychotropic drugs or other medications that may affect cognition, such as anticholinergics, opioids, benzodiazepines, antidepressants, muscle relaxants, and antiepileptics. Exclusion Criteria: * Parkinson's disease. * Linguistic single-domain MCI (suspected onset of primary progressive aphasia). * Other neurological conditions potentially associated with cognitive impairment (e.g., previous stroke or traumatic brain injury). * Significant laboratory abnormalities potentially associated with cognitive impairment (e.g., low levels of vitamin B12 or folate, or values indicative of thyroid disorders). * Primary psychiatric disorders. * Alcohol or substance use disorder in the previous 10 years. * Severe behavioral disturbances limiting group participation. * Hearing or visual impairments that may interfere with assessment or treatment. * Medical conditions that may interfere with completion of the study. * Exposure, during the study period, to other neuropsychological rehabilitation interventions. * Patient's refusal to sign the informed consent.
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What it tests

  • Multimodal Group Cognitive Rehabilitation Intervention
  • Active Control
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Where

2 sites
Casa di Cura Igea
Milan, Italy
Casa di Cura Igea
Milan, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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