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LLM-Generated Plain-Language Patient Synopses to Improve Comprehension in Hematology and Oncology (oncOPAL)

RecruitingNAAges 18 Years - anyAllTechnical University of Munich
NCT07519811 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study tests whether patients with blood cancer or other cancers better understand their medical information when it is rewritten in plain language by an artificial intelligence (AI) system. When patients are discharged from the hospital, they receive a medical letter summarizing their diagnosis, treatment, and next steps. These letters are often written in technical language that is difficult for patients to understand. In this study, an AI language model running on the hospital's own secure servers rewrites parts of this letter into simpler language. A physician checks the simplified version before the patient receives it. Patients are randomly assigned to one of two groups. One group receives both the standard medical letter and the AI-simplified version. The other group receives the standard letter only. A separate group of patients who do not speak German well will receive a s

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older * Inpatient of the Department of Medicine III (Hematology/Oncology) at TUM University Hospital (Klinikum rechts der Isar), Munich, Germany * Receipt of a discharge letter including the sections Current Status, Medical History, Epicrisis, and Further Management as part of routine clinical care * Capacity to provide informed consent * Written informed consent following the consent procedure Exclusion Criteria: * Cognitive impairment precluding independent assessment of comprehension (e.g., dementia, severe encephalopathy) * Participation in another study with potential influence on the study endpoints * Lack of capacity to provide informed consent * Refusal to participate in the study
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What it tests

  • LLM-Generated Plain-Language Patient Synopsis
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Where

1 site
Technical University Munich
Munich, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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