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Oral Biopsy Bleeding in Patients on Direct Oral Anticoagulants (DOACs)

Recruitingn/aAges 18 Years - anyAllUniversity of Pisa
NCT07520890 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Direct oral anticoagulants (DOACs) are increasingly used, but evidence on bleeding risk during oral soft tissue biopsy is limited. This prospective case-control study compared intraoperative, perioperative, and postoperative bleeding in 50 patients on uninterrupted DOAC therapy versus 50 anticoagulant-naive controls undergoing standardized oral soft tissue biopsy with suturing. All bleeding events were managed with local haemostatic measures. The study aims to determine whether DOAC continuation is safe for this procedure.

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📋 Eligibility rules (as published)
Inclusion Criteria: * capacity to understand and sign informed consent; * documented indication for oral soft tissue biopsy Exclusion Criteria: * inability to provide consent; * congenital or acquired coagulopathy (including haemophilia, von Willebrand disease, thrombocytopenia, or hepatic cirrhosis); * active antiplatelet therapy other than low-dose aspirin
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What it tests

  • Not listed
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Where

1 site
University of Pisa
Pisa, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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