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Early vs Delayed Extracorporeal Shock Wave Lithotripsy for Residual Stones After Percutaneous Nephrolithotomy

RecruitingNAAges 18 Years - 70 YearsAllBeni-Suef University
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In plain words

What the trial is, and whether it could suit you

Residual renal stone fragments remain a common clinical issue following percutaneous nephrolithotomy (PCNL), with reported incidence ranging from 10% to 30%. These fragments may act as a nidus for recurrent stone formation, infection, or obstruction, necessitating further intervention. Extracorporeal shock wave lithotripsy (ESWL) is widely used as a non-invasive treatment option for such residual stones; however, the optimal timing of ESWL after PCNL remains unclear. Early application of ESWL may enhance stone clearance before fragment embedding or encrustation occurs, but it could be associated with increased risk of bleeding or infection due to incomplete renal healing. Conversely, delayed ESWL allows for better tissue recovery but may permit stone growth or persistence of symptoms. This prospective randomized comparative study aims to evaluate the optimal timing of ESWL after PCNL i

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18-70 years. * Single or multiple residual renal stones โ‰ค15 mm after PCNL. * Normal renal function (serum creatinine \<1.5 mg/dL). * No active UTI. Exclusion Criteria: * Bleeding disorders or anticoagulant therapy. * Obstructed drainage or active sepsis. * Stones \>15 mm or requiring secondary PCNL.
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What it tests

  • Extracorporeal shock wave lithotripsy (ESWL)
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Where

1 site
Beni-Suef university hospital
Banฤซ Suwayf, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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