AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Autologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial Hemorrhage

RecruitingNAAges 6 Months - 18 YearsAllNational Children's Hospital, Vietnam
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study evaluates the safety and preliminary efficacy of autologous bone marrow mononuclear cell transplantation combined with rehabilitation in children with neurological sequelae caused by hypoxic-ischemic brain injury or intracranial hemorrhage. Participants in the intervention group will receive autologous bone marrow aspiration, mononuclear cell transplantation via intrathecal route, and rehabilitation, while the control group will receive rehabilitation alone. Outcomes will be compared between groups over follow-up time points.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Children diagnosed with cerebral palsy * Age from 12 months to 72 months * Cerebral palsy caused by hypoxic-ischemic brain injury or intracranial hemorrhage * Gross Motor Function Classification System (GMFCS) level III to V * Completed required laboratory tests according to the study protocol * Written informed consent obtained from the child's parent or legal guardian Exclusion Criteria: * Children with acute infection at the time of screening or enrollment * Children with severe coagulopathy or contraindications to bone marrow aspiration * Children with severe systemic diseases (e.g., severe cardiac, hepatic, or renal failure) * Children with contraindications to anesthesia or intrathecal transplantation procedures * Children with a history of malignancy * Children who are unable to participate in or complete the rehabilitation program * Parents or legal guardians who do not provide informed consent
๐Ÿ’Š

What it tests

  • Autologous Bone Marrow Mononuclear Cell Transplantation
๐Ÿ“

Where

1 site
Vietnam National Children's Hospital
Hanoi, Vietnam
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy