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Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure

RecruitingPhase 4Ages 18 Years - anyAllInstitute for Clinical and Experimental Medicine
NCT07527156 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will evaluate the feasibility and safety of achieving therapeutic concentrations of beta-hydroxybutyrate using continuous infusion of D-beta-hydroxybutyrate monoester administered via a nasogastric tube in patients with acutely decompensated heart failure with reduced left ventricular ejection fraction.

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📋 Eligibility rules (as published)
Inclusion Criteria: * LVEF \<35% * Acute heart failure with low cardiac output syndrome or cardiogenic shock Exclusion Criteria: * Severe liver failure * Severe acidosis * Inability to insert nasogastric tube * Gastric paralysis / ileus * Repeated vomiting * Severe hypokalemia
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What it tests

  • Ketone Monoester (KE)
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Where

1 site
Institute for Clinical and Experimental Medicine (IKEM)
Prague, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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