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Comparison Of Effectiveness Of Intralesional Injectioms Of 5 Flourouracil Alone Verses Its Cpmbination With Cryotherapy In The Treatment Of Keloids

RecruitingEARLY Phase 1Ages 18 Years - 50 YearsAllCombined Military Hospital (CMH) institute of Med…
NCT07531056 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn how well intralesional 5 fluorouracil with cryotherapy works to treat keloids as compared to intralesional 5 fluorouracil alone on keloids. It will also learn about the safety of both these treatments. The main questions it aims to answer are: * What well does cryotherapy followed by intralesional 5 fluorouracil (5FU) work to treat keloids as compared to 5 fluorouracil (5FU) alone? * What is participant's satisfaction when treated with cryotherapy followed by intralesional 5 fluorouracil (5FU) as compared to 5 fluorouracil (5FU) alone? * What skin problems do participants have when treated with cryotherapy followed by intralesional 5 fluorouracil (5FU) and 5 fluorouracil (5FU) alone? Researchers will compare cryotherapy followed by intralesional 5 fluorouracil (5FU) with 5 fluorouracil (5FU) alone to see how well both work. Participants will

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients willing to participate in the study * Patients of age group of 18 -50 years. * Patients having symptomatic keloids i.e., having pain, pruritus, restriction of movement, scar tension or disfigurement. Exclusion Criteria :• Pregnant women or lactating women * Patients with history of hepatic, renal, cardiac diseases or chronic diarrhea. * Patients on immunosuppressant medications due to other diseases * Patients having myelosuppression checked by CBC. * Patient taking warfarin. * Patients with history of hypersensitivity to 5FU.
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What it tests

  • Cryotherapy will be done followed by intralesional injection of 5-fluorouracil
  • Intralesional 5-fluorouracil
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Where

1 site
CMH Bahawalpur
Chak Four Hundred Fifty-four, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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