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Multicomponent Prehabilitation in Older Adults With Breast Cancer

RecruitingNAAges 65 Years - anyAllFundacion Miguel Servet
NCT07531836 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications. Prehabilitation programs have emerged as a promising strategy to improve physical function and clinical outcomes; however, evidence in geriatric oncology remains limited, particularly regarding the role of biological markers in predicting response to such interventions. This study aims to evaluate the effectiveness of a multicomponent prehabilitation program in older adults with breast cancer, focusing on functional status, clinical outcomes, and quality of life. In addition, the study seeks to characterize biological markers associated with frailty and treatment response, with the goal of identifying potential predictors of benefit from prehabilitation. Participants will undergo a structured prehabilitation intervention including physical ex

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥65 years * Diagnosis of breast cancer requiring elective surgery with curative intent * Candidate for prehabilitation program before surgery * Ability to walk (with or without assistive devices) * Ability to provide informed consent Exclusion Criteria: * Urgent or emergency surgery * Severe cognitive impairment precluding participation in the intervention * Severe functional dependency (e.g., bedridden patients) * Medical contraindication to physical exercise * Life expectancy \<3 months
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What it tests

  • Home-based Multicomponent Prehabilitation (Vivifrail)
  • Supervised Multicomponent Prehabilitation
  • Comprehensive Geriatric Assessment and Optimization
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Where

1 site
Hospital Universitario de Navarra
Pamplona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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