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Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery

RecruitingNAAges 18 Years - 50 YearsAllDamascus University
NCT07532161 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions. The etiology of this condition varies and may include vertical maxillary excess, short upper lip, hyperactive upper lip, gingival enlargement, or altered passive eruption. Lip Repositioning Surgery is one of the minimally invasive esthetic surgical procedures used to reduce the amount of gingival display during smiling. Despite its effectiveness, this surgery may be associated with challenges such as pain, swelling, delayed wound healing, and the possibility of postoperative relapse over time, which could compromise both esthetic and functional outcomes. To overcome these challenges and enhance surgical outcomes, adjunctive techniques have been introduced to promote healing and determine whether enhancing the biological h

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients of both genders. 2. Patients presenting with a gummy smile in the maxillary anterior region (more than 3 mm) due to upper lip hypermobility. 3. Age 18-50 years. 4. Systemically healthy individuals, classified as ASA physical status I or II according to the American Society of Anesthesiologists (ASA) classification; that is, patients without systemic disease or with mild, well-controlled systemic conditions. 5. Patients with good oral hygiene, defined as an O'Leary Plaque Index ≤ 40%. 6. No previous lip repositioning surgery. Exclusion Criteria: 1. Pregnancy and lactation. 2. Individuals with a previous history of receiving facial Botox or filler injections. 3. Systemic diseases or conditions that contraindicate the use of local anesthesia. 4. Any physical condition that impairs the ability to perform proper oral hygiene measures. 5. Patients who are smokers or alcohol consumers. 6. Inability or unwillingness to cooperate. 7. In adequate width of attached gingiva. 8. Vertical maxillary excess (moderate to severe) requiring orthognathic intervention. 9. Short upper lip 10. Gingival display primarily caused by altered passive eruption requiring crown lengthening.
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What it tests

  • Liquid Platelet-Rich Fibrin group
  • low-level laser group
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Where

1 site
Faculty of Dentistry, Damascus university , Syria.
Damascus, Syria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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