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A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

RecruitingPhase 2, Phase 3Ages 18 Years - anyAllPriovant Therapeutics, Inc.
NCT07532603 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 years 2. Scalp biopsy consistent with LPP 3. Active and symptomatic LPP at screening and baseline- 4. Weight \> 40 kg to \< 130 kg with BMI ≤ 45 kg/m2 Exclusion Criteria: 1. History of: Lymphoproliferative disorder; Active malignancy; History of cancer within 5 years prior to baseline (exceptions for basal cell carcinoma, squamous cell carcinoma, ductal carcinoma in situ of the breast, carcinoma in situ of the uterine cervix, or thyroid cancer). 2. High risk of thrombosis or cardiovascular disease 3. High risk of herpes zoster 4. Active or recent infection
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What it tests

  • Oral Brepocitinib
  • Placebo
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Where

61 sites
Clinical Trial Site
Birmingham, United States
Clinical Trial Site
Phoenix, United States
Clinical Trial Site
Scottsdale, United States
Clinical Trial Site
Irvine, United States
Clinical Trial Site
Oakland, United States
Clinical Trial Site
Sacramento, United States
Clinical Trial Site
San Francisco, United States
Clinical Trial Site
Denver, United States

…and 53 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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