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Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients

RecruitingNAAges any - anyAllMilitary Hospital 103
NCT07532694 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis. Eighty participants will be allocated to two parallel groups: scaling and root planing (SRP) with adjunctive diode laser therapy or SRP alone. Clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles will be assessed at baseline and during follow-up. The study aims to determine whether adjunctive diode laser therapy provides superior clinical and biological improvement compared with SRP alone.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Kidney transplant recipients aged 18 years or older. * Diagnosis of periodontitis according to the study case definition. * Medically stable and able to undergo non-surgical periodontal treatment. * Willing and able to provide written informed consent and attend follow-up visits. Exclusion Criteria: * \- Periodontal treatment or systemic antibiotic use within the predefined exclusion window in the protocol. * Acute oral infection requiring urgent treatment. * Pregnancy or lactation, if excluded by the approved protocol. * Serious systemic condition or clinical instability judged by investigators to preclude study participation. * Inability to comply with study procedures or follow-up schedule.
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What it tests

  • Scaling and Root Planing
  • Diode Laser
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Where

2 sites
103 Military Hospital
Hanoi, Vietnam
Vietnam Military Medical University
Hanoi, Vietnam
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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