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Gas6 and Soluble MerTK in Periodontal Diseases

Recruitingn/aAges 18 Years - anyAllAbant Izzet Baysal University
NCT07535177 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Individuals without systemic diseases that may affect periodontal tissues (such as cardiovascular diseases, atherosclerosis, immune system disorders, rheumatoid arthritis, obesity, cancer, and diabetes) * Individuals who have not used antibiotics within the last 3 months * Individuals not taking any medications known to affect periodontal tissues * Individuals without infectious diseases such as HIV, hepatitis B virus (HBV), or tuberculosis * Individuals with at least 16 natural teeth, excluding third molars * Individuals aged 18 years and older Exclusion Criteria: * Pregnant or lactating individuals * Individuals who have received periodontal treatment within the last 6 months * Current smokers
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What it tests

  • gingival crevicular fluid collection
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Where

1 site
Bolu Abant Izzet Baysal University Faculty of Dentistry
Bolu, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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