🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.

Recruitingn/aAges 5 Years - 17 YearsAllAalborg University Hospital
NCT07535619 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the study aims to investigate if the microbiota is different according to the severity of DUI and if the microbiota is changed throughout treatment of DUI. A follow-up study will as well be performed on healthy children to investigate how the microbiota evolves with increasing age and pubertal stage. Children with OAB and DUI will be recruited from involved pediatric departments, and specimen in the form of urine, perineal/preputial swabs, and feces will be collected according to the protocol.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Overactive bladder as per International Children's Continence Society criteria (cases only). * At least two wet days per week (cases only). * No prior pharmacological treatment of OAB and DUI (cases only). * No lower urinary tract symptoms (healthy participants only). * Negative urine dipstick test Exclusion Criteria: * No known urogenital abnormality affecting the lower urinary tract function. * No known gastrointestinal or neurological diseases. * No use of systemic drugs within five half-lives of the drug. * No use of systemic antibiotics within three months before inclusion * No current urinary tract infection. * No urinary tract infection within the last three months prior to inclusion. * No current constipation. * Abnormal uroflowmetry (healthy participants only).
💊

What it tests

  • Not listed
📍

Where

4 sites
Department of Pediatrics, Aalborg University Hospital
Aalborg, Denmark
Department of Pediatrics, Aarhus University Hospital
Aarhus, Denmark
Department of Pediatrics, Regional Hospital West Jutland
Herning, Denmark
Department of Pediatrics, North Denmark Regional Hospital
Hjørring, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy