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← Trials
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Antihistamine for Prevention of HTR After Blood Primed CPB

RecruitingPhase 4Ages 1 Year - 7 YearsAllKasr El Aini Hospital
NCT07536152 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will be a randomized, double-blinded, placebo-controlled study conducted at a university hospital. Forty children undergoing elective repair of a congenital heart defect will be included. The patients will be randomly allocated (20 patients per group) to receive a single intravenous dose of combined chlorpheniramine or normal saline immediately after separation from CPB, before protamine administration.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Acyanotic congenital heart disease. * Age :1 -7 years. * Genre: both. Exclusion Criteria: * Redo patient. * History of allergy to antihistamines. * Bleeding disorders with INR \> 1.5 and/or platelets \< 50,000. * Emergency procedure.
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What it tests

  • Antihestamine
  • Placebo
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Where

1 site
Misr Universty for Scince and Technology
Giza, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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