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Doppler Flow in Tubal Ectopic Pregnancy in Diagnosis as a Predictor of Treatment Success - Conservative and MTX Treatment

Recruitingn/aAges 18 Years - 45 YearsFemaleMeir Medical Center
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In plain words

What the trial is, and whether it could suit you

The study "Doppler Flow in Tubal Ectopic Pregnancy as a Predictor of Treatment Success: Conservative and MTX Therapy" aims to evaluate the role of Doppler ultrasound parameters (RI, PI, and PSV) in predicting treatment success for tubal ectopic pregnancies. Ectopic pregnancies, affecting \~2% of all pregnancies (98% in fallopian tubes), pose significant risks, including rupture and maternal mortality. Diagnosis is typically achieved via transvaginal ultrasound, with Doppler imaging enhancing accuracy by detecting characteristic vascular patterns. Management options include conservative monitoring, methotrexate (MTX) therapy, or surgery, based on clinical stability, ฮฒ-hCG levels, and ultrasound findings. While ฮฒ-hCG levels are a known predictor of MTX treatment failure, there is no consensus on an optimal threshold. Prior research suggests increased vascularization on Doppler ultrasound

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion criteria: * Tubal ectopic pregnancy * Hemodynamically stable, with no suspicion of rupture, * Eligible for MTX or conservative therapy. Exclusion criteria: * Intrauterine pregnancy * Hemodynamic instability * Suspected tubal rupture * Other ectopic pregnancy: CSP, Ovarian, heterotopic pregnancy
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What it tests

  • Not listed
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Where

1 site
Meir Medical Center
Kfar Saba, Israel
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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