Pinoxin for the Prevention of Radiation-Induced Skin Injury

Inclusion Criteria: 1. Age ≥ 18 years, regardless of gender. 2. Pathologically diagnosed with a malignant tumor. 3. Scheduled to receive long-course radiotherapy with a total dose of ≥50 Gy, in accordance with standard treatment guidelines. 4. No prior history of radiotherapy. 5. Has provided signed and dated informed consent, indicating that the patient has been informed of all relevant aspects of the study. 6. Patients who are willing and able to comply with scheduled visits, treatment plans, laboratory tests, and other study procedures. Exclusion Criteria: 1. History of dermatologic conditions (e.g., vitiligo, psoriasis, etc.) or collagen vascular diseases. 2. Planned hypofractionated radiotherapy regimen. 3. Recent use (e.g., within 3 months) of similar topical protective agents. 4. Known hypersensitivity to any related components or materials. 5. Immunodeficiency disorders. 6. Women who are pregnant or lactating. 7. Any other condition that, in the investigator's judgment, may compromise patient safety or protocol compliance. This includes severe concomitant illnesses (including psychiatric disorders) requiring active treatment, significant laboratory abnormalities, or significant social/familial factors.