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Bright Light Therapy During Inpatient Cocaine Detoxification

RecruitingNAAges 18 Years - anyAllHôpital le Vinatier
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In plain words

What the trial is, and whether it could suit you

Cocaine is a major psychostimulant used to induce a state of euphoria, improved self-confidence and resistance to fatigue, with suppression of sleep. The progressive use of cocaine leads to a potentially severe addictive process, with sometimes dramatic social repercussions, a major disruption of major physiological functions, such as sleep or nutrition, and risks of psychiatric, neurological or cardiovascular complications. Today, cocaine addiction is considered to be a growing societal problem, due to the fact that the use of this drug is becoming commonplace. There is no validated consensus or protocol for the management of cocaine addiction and no validated pharmacological treatment. The main therapeutic strategy for cocaine addiction is to organize a supervised cessation of use (withdrawal), followed by assistance in maintaining cessation. Withdrawal is a sensitive period that freq

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female, 18 years of age or older * DSM-5 criteria for cocaine use disorder * Positive urine screen for cocaine * Hospitalization for supervised cocaine detoxification planned within the four upcoming weeks * The patients must be insured or beneficiary of a health insurance plan * Signed and dated informed consent document(s) indicating that the subject has been informed of all pertinent aspects of the trial Exclusion Criteria: * Non-stabilized opioid use disorder or other psychostimulant use disorder (e.g., amphetamine, met-amphetamine, cathinones, methylphenidate…) * Non-stabilized psychiatric disorder or somatic disease, which is considered incompatible with inclusion by the investigator * Current treatment with methylphenidate, modafinil, solriamfetol, melatonin pitolisant, naltrexone, or bupropion. * Contraindication to light therapy: retinopathy, pigmentary retinitis, diabetic retinopathy, macular degeneration, glaucoma, recent (i.e., less than three month) eye surgery. (If there is any doubt about an ophthalmological contraindication, a specialist opinion will be requested) * Tutorship * Pregnant or breastfeeding women: the performance of a pregnancy test before inclusion for women of childbearing age * Persons deprived of their liberty by a judicial or administrative decision * Persons participating in other research with an exclusion period still in progress at pre-inclusion
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What it tests

  • Medical light therapy device
  • Medical light therapy device sham
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Where

1 site
Centre Hospitalier Le Vinatier
Bron, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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