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Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis

RecruitingNAAges 18 Years - anyAllUniversity Medical Center Ho Chi Minh City (UMC)
NCT07546565 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a randomized controlled trial conducted at University Medical Center Ho Chi Minh City to evaluate the role of mechanical bowel preparation (MBP) in patients undergoing laparoscopic right hemicolectomy with totally intracorporeal anastomosis for colon cancer. Mechanical bowel preparation is commonly used before colorectal surgery to reduce bowel contents and potentially decrease the risk of postoperative infections. However, its benefit remains controversial, particularly in intracorporeal anastomosis, where intra-abdominal contamination may influence surgical outcomes. In this study, eligible patients will be randomly assigned to one of two groups: with or without mechanical bowel preparation before surgery. The study aims to compare intraoperative events, postoperative complications, and recovery outcomes between the two groups. The primary outcome is the rate of surgic

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with colon cancer stage I-III according to the TNM classification * Patients undergoing elective right hemicolectomy or extended right hemicolectomy with totally intracorporeal anastomosis at University Medical Center Ho Chi Minh City * Postoperative histopathological confirmation of adenocarcinoma Exclusion Criteria: * Patients undergoing emergency surgery * Contraindications to mechanical bowel preparation (e.g., bowel obstruction, subobstruction, bowel perforation, or peritumoral abscess) * Contraindications to laparoscopic surgery (American Society of Anesthesiologists \[ASA\] physical status IV or V) or to intracorporeal anastomosis * Distant metastasis at the time of surgery (stage IV according to the TNM classification) * Recurrent colon cancer after prior surgery * Synchronous primary malignancies in other organs * Patients undergoing palliative surgery or surgery for tumor-related complications (non-curative intent) * Inability to complete follow-up or be contacted
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What it tests

  • Mechanical Bowel Preparation
  • No mechanical bowel preparation
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Where

1 site
University Medical Center HCMC
Ho Chi Minh City, Vietnam
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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