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Effectiveness of tDCS in Paediatric Amblyopia.

RecruitingNAAges 4 Years - 14 YearsAllUniversidad de Murcia
NCT07547670 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized, double-blind clinical trial is to determine whether transcranial direct current stimulation (tDCS) can effectively and safely improve vision in children aged 4-14 years with strabismic or anisometropic amblyopia that has not responded to conventional patching therapy. The main questions it aims to answer are: Does tDCS produce significant and sustained improvements in visual acuity, contrast sensitivity, and stereopsis in children with amblyopia? Is tDCS a safe, well-tolerated, and faster alternative or complementary treatment compared with standard occlusion therapy? Does tDCS induce functional and structural changes in the visual cortex associated with increased neuroplasticity, including modulation of GABAergic activity? If there is a comparison group: Researchers will compare active tDCS with sham (placebo) stimulation to see if active treatment lea

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📋 Eligibility rules (as published)
Inclusion Criteria: * Children aged 4-14 years. * Strabismic amblyopia resistant to patching (PEDIG criteria). * Anisometropic amblyopia resistant to patching (PEDIG criteria). Exclusion Criteria: * Ocular pathology. * Nystagmus. * Mental disability. * Cognitive delay. * Neurological problems incompatible with treatment. * Pacemakers. * Intracranial electrodes. * Implanted defibrillators. * Cranial pathologies. * Cranial lesions. * Withdrawal will occur upon adverse events, protocol deviation, refusal, or loss to follow-up.
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What it tests

  • tDCS
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Where

1 site
University of Murcia
Murcia, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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