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Transoral and Cervical Ultrasound of Patients With Suspected Oropharyngeal Cancer

RecruitingNAAges 18 Years - anyAllTobias Todsen
NCT07548268 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Introduction The current diagnostic approach for patients with suspected oropharyngeal cancer involves a combination of clinical examination, tissue sampling, and relevant cross-sectional imaging. Previous studies have shown that transoral and cervical ultrasound (US) of the palatine and lingual tonsils has a better diagnostic accuracy than clinical investigation and magnetic resonance imaging (MRI) in patients with suspected oropharyngeal cancer, but it has not been established whether adding this scan to the diagnostic workup has a clinical impact. Methods A randomized controlled study, including 170 patients at four different Head and Neck Hospital departments in Denmark. One group receives standard diagnostics (control group), and the other group receives standard diagnostics supplemented by transoral and cervical ultrasound of the lingual and palatine tonsils. The diagnostic accura

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📋 Eligibility rules (as published)
Inclusion Criteria: Referred to outpatient cancer clinic with one of the following: * A scan (MR, CT, PET/CT) suggesting malignancy in the oropharynx. This being asymmetric metabolic activity on PET/CT, a tumor or asymmetry of the palatine and lingual tonsils on MR and CT (7). * Tumor suspicious findings (erosion/ulcus, tonsil asymmetry/hypertrophy). * Tumor-suspicious symptoms (pain of the oropharynx) * \> 18 years of age. * Ability to understand and give informed consent. Exclusion Criteria: * • Prior oropharyngeal cancer * Prior radiation to the head and neck area
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What it tests

  • Ultrasound of the oropharynx
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Where

4 sites
Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital
Aarhus, Denmark
Department of Otorhinolaryngology, Head and Neck Surgery & Audiology
Copenhagen, Denmark
Department of Otorhinolaryngology, Head and Neck Surgery & Audiology Northzealand Hospital
Hillerød, Denmark
Department of ORL - Head & Neck Surgery and Audiology, Zealand University Hospital,
Køge, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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