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Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study

Recruitingn/aAges any - anyAllVastra Gotaland Region
NCT07550218 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS). Preterm infants often have immature lungs and a deficiency of surfactant, a substance that helps keep the lungs open and supports oxygen exchange.Surfactant can be delivered to the lungs using different techniques, including INSURE (brief intubation), LISA (via a thin catheter), SALSA (via a laryngeal mask airway), and traditional administration via endotracheal intubation followed by mechanical ventilation. The main question this study aims to answer is:Which method of surfactant administration is associated with better clinical outcomes in preterm infants with RDS?The study will prospectively collect clinical data on infants receiving surfactant as part of standard care, with long-term follow-up using data from the Swedish Neona

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient has received surfactant by any administration method * Gestational age below 37 weeks' * First surfactant treatment given before 48 hours of age * Confirmed or suspected diagnosis of respiratory distress syndrome (RDS) Exclusion Criteria: • Not fulfilling above inclusion criteria
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What it tests

  • Not listed
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Where

1 site
Neonatal Intensive Care Unit, Sahlgrenska University Hostal
Gothenburg, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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