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Chemotherapy-Induced Hearing Loss and Health Inequality

Recruitingn/aAges 18 Years - anyAllLancaster University
NCT07553481 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This project aims to understand how platinum-based chemotherapy affects hearing function in cancer patients from different socioeconomic backgrounds in the North West of England. Platinum-based chemotherapy drugs, such as cisplatin, are ototoxic, meaning that they cause permanent damage to the hair cells of the ear, resulting in hearing loss. Patients from more deprived backgrounds face additional risk factors to their hearing health, including limited healthcare access, greater occupational noise exposure, and poorer overall health, making them more vulnerable to hearing loss. This is especially concerning as hearing loss can make communication more challenging, which creates a greater reliance on cognitive processes such as thinking and memory to navigate social interactions. This challenge is exacerbated when individuals experience cognitive dysfunction related to chemotherapy, commo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients receiving platinum-based chemotherapy drugs * Living and treated within North West England * Able to complete an online hearing and cognitive test * Fluent in English Exclusion Criteria: * Following cancer types: brain tumour/metastasis, head + neck, skin cancers around the ear, and adenoid cystic carcinoma of the auditory cortex * World Health Organisation performance status score of 3 or more * Stage 4 cancer * History of childhood deafness * Current or recent ear infections * Cochlear implant user * Known neurological impairment (e.g., stroke, traumatic brain injury, dementia) * Patients who look capacity to consent or complete study tasks
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What it tests

  • Not listed
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Where

1 site
Lancaster University
Lancaster, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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