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Evaluation Criteria, Diagnostic Criteria, Surgical Indications, and Establishment of Surgical Standards for "Cerebral Tinnitus Syndrome" Caused by Internal Jugular Vein Stenosis.

RecruitingNAAges 18 Years - 75 YearsAllBeijing Shijitan Hospital, Capital Medical Univerโ€ฆ
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In plain words

What the trial is, and whether it could suit you

"Cerebral Tinnitus," also known as "cranial tinnitus," refers to the patient-reported perception of intracranial sounds. It often presents as "Cerebral Tinnitus Syndrome," which includes symptoms such as tinnitus with hearing loss, headaches, a heavy head sensation, blurred vision, neck and shoulder discomfort, sleep disturbances, anxiety, and depression. Due to limited awareness of cerebral tinnitus, patients frequently seek treatment across multiple facilities without success, severely impacting their and their families' lives and work. Xunming Ji and colleagues have pointed out that cerebral tinnitus results from stenosis of the cerebral or internal jugular veins (IJVS), which impairs cerebral venous outflow and the clearance of metabolic "waste," leading to chronic metabolic damage to brain cells. Currently, studies on the diagnosis and treatment of IJVS-induced cerebral tinnitus, b

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 75 years, with no gender restriction. 2. Presence of one or more symptoms associated with "Cerebral Tinnitus Syndrome," with a duration of at least 3 months. 3. Following a detailed medical history and comprehensive physical examination, other known causes of cerebral tinnitus are preliminarily excluded, with suspected internal jugular vein stenosis (IJVS) as the cause. 4. Imaging studies (e.g., jugular ultrasound, cervical venous CT venography (CTV)) show significant stenosis in the internal jugular vein (stenosis degree โ‰ฅ50%). 5. The patient has provided informed consent and voluntarily agrees to participate in the study, with a signed informed consent form. Exclusion Criteria: 1. Patients with a history of cranial surgery or diagnosed intracranial space-occupying lesions. 2. Patients with severe cardiac, hepatic, or renal insufficiency, or other systemic diseases. 3. Patients who have undergone any surgical or interventional procedures affecting jugular venous flow within the last 6 months. 4. Patients with a history of psychiatric disorders or cognitive impairment who cannot complete study evaluations. 5. Pregnant or breastfeeding women.
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What it tests

  • Atlas Transverse Process Mastoidectomy with Lysis and Perfusion
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Where

1 site
Beijing Shijitan Hospital, Capital Medical University
Beijing, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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