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Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation

RecruitingNAAges 18 Years - 70 YearsAllKalliopi Anna Poulia
NCT07561138 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice (Group C) on nutritional status, body composition and functional status in patients awaiting liver transplantation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * End-stage liver disease, diagnosed by transient elastography (FibroScan) or imaging-based evaluation with compatible clinical picture * Referred for liver transplantation and evaluated to have a high likelihood of being listed, according to primary hepatologist assessment, or already listed for liver transplantation * No prior formal dietary advice Exclusion Criteria: * Age \< 18 years old * Estimated waiting time for liver transplantation \< 3 months * Estimated life expectancy \< 3 months * Chronic kidney disease requiring protein restriction * Exercise contraindicated (e.g., active or recent variceal bleeding, severe grade of hepatic encephalopathy, refractory ascites, etc.) * Unstable or severe psychiatric disorder * Pregnancy or lactation * Inability to provide written informed consent
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What it tests

  • Diet with even protein distribution plus exercise program
  • Diet with skewed protein distribution plus exercise program
  • Standard dietary and physical activity advice
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Where

2 sites
Laiko General Hospital of Athens
Athens, Greece
Agricultural University of Athens
Athens, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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