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Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty

RecruitingNAAges 18 Years - 80 YearsAllHitit University
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In plain words

What the trial is, and whether it could suit you

Total knee arthroplasty (TKA) is associated with severe postoperative pain that delays mobilization, prolongs hospital stay, and reduces patient satisfaction. Regional analgesia techniques have gained prominence due to their opioid-sparing effects and favorable complication profiles compared to general anesthesia. While adductor canal block (ACB) effectively manages anterior knee pain with preserved motor function, posterior knee pain remains a challenge. IPACK (Infiltration between the Popliteal Artery and Capsule of the Knee) and the Biceps Femoris Short Head (BiFeS) block are techniques targeting posterior capsule innervation without causing motor block.This prospective study aims to compare the postoperative analgesic efficacy of ultrasound-guided ACB+IPACK versus ACB+BiFeS block combinations in patients undergoing TKA under spinal anesthesia. Patients (ASA I-III, age 18-80, BMI ≤35)

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📋 Eligibility rules (as published)
Inclusion Criteria: * Scheduled for primary total knee arthroplasty surgery * ASA physical status classification I-III * Hemodynamically stable * Age ≥ 18 years and ≤ 80 years * BMI ≤ 35 kg/m² * Signed written informed consent form Exclusion Criteria: * Revision total knee arthroplasty surgery * Simultaneous bilateral total knee arthroplasty * BMI \> 40 kg/m² * ASA physical status classification 4-5 * Inability to perform NRS pain scoring * Known allergy to local anesthetics * Pregnancy or breastfeeding * Age \< 18 or \> 80 years * Uncontrolled anxiety disorder * Alcohol or drug dependency * Neuromuscular disease or peripheral nerve disease * High-dose opioid use within 3 days prior to surgery * Widespread chronic pain syndrome * Diabetes mellitus * Hepatic or renal insufficiency * Coagulation disorders * Current use of anticoagulant medications * Infection at the peripheral nerve block needle insertion site * Refusal to participate in the study
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What it tests

  • ACB+IPACK Group
  • ACB+BiFeS Group
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Where

1 site
Hitit University
Çorum, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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