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โ† Trials
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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3Ages 18 Years - anyAllImmuneering Corporation
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the safety and efficacy of atebimetinib in combination with modified GnP compared with SOC GnP alone.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Must be โ‰ฅ18 years of age * Must have confirmed diagnosis according to AJCC staging as follows: * Metastatic pancreatic adenocarcinoma within 12 weeks prior to screening * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 * Participants must be treatment naive as follows: * First-line PDAC participants will have received no previous systemic anti-cancer therapy * Must have evidence of measurable disease (at least one target lesion) per RECIST v1.1 criteria * Adequate organ function, hepatic function, coagulation studies and protocol determined clinical laboratory values Exclusion Criteria: * Inability to swallow oral medications * Participant has squamous, adenosquamous, neuroendocrine (carcinoid, islet cell) or acinar pancreatic carcinoma * Participants with only locally advanced disease * Symptomatic, untreated, or actively progressing known central nervous system (CNS) metastases
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What it tests

  • Atebimetinib
  • GnP
  • mGnP
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Where

70 sites
Clearview Cancer Institute
Huntsville, United States
City of Hope
Phoenix, United States
City of Hope
Duarte, United States
University of California San Diego
San Diego, United States
Poudre Valley Health Care, Inc
Fort Collins, United States
Rocky Mountain Cancer Centers
Lone Tree, United States
Medical Oncology Hematology Consultants
Newark, United States
Hematology Oncology Associates of the Treasure Coast
Port Saint Lucie, United States

โ€ฆand 62 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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