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Effects of Isometric, Isotonic, and Eccentric VMO Exercises in Patellofemoral Pain Syndrome

RecruitingNAAges 18 Years - 50 YearsAllFirat University
NCT07562425 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patellofemoral pain syndrome (PFPS) is a common musculoskeletal condition characterized by anterior knee pain, especially during activities such as stair climbing, squatting, running, and prolonged sitting. Weakness or delayed activation of the vastus medialis oblique (VMO) muscle is considered an important contributing factor in the development of PFPS. This study aims to compare the effects of three different types of VMO strengthening exercises (isometric, isotonic, and eccentric) applied within the terminal knee extension range (0-30°) on pain, functional performance, and muscle architecture in individuals with PFPS. Participants will be randomly assigned to one of three exercise groups. All participants will receive a standardized physiotherapy program, including heat therapy, TENS, and therapeutic ultrasound, followed by group-specific VMO strengthening exercises. The interventio

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged between 18 and 40 years * Clinically diagnosed with patellofemoral pain syndrome * Presence of anterior knee pain for at least 3 months * Pain during activities such as stair climbing, squatting, running, or prolonged sitting * Pain intensity of at least 3/10 on the Visual Analog Scale (VAS) * Willingness to participate and provide written informed consent Exclusion Criteria: * History of knee trauma or surgery * Meniscal injury, ligament injury, or knee instability * Advanced osteoarthritis * Neurological disorders * Rheumatologic diseases * Participation in a structured knee rehabilitation program within the last 6 months * Pregnancy
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What it tests

  • Isometric VMO Exercise
  • Isotonic VMO Exercise
  • Eccentric VMO Exercise
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Where

1 site
Firat University
Elâzığ, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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