🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

JAK2 Expression in Androgenetic Alopecia Before and After Topical Minoxidil

RecruitingNAAges 18 Years - 50 YearsMaleKasr El Aini Hospital
NCT07563036 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Androgenetic alopecia is a common form of progressive hair loss. This prospective single-arm pre-post interventional study aims to assess tissue Janus Kinase 2 (JAK2) expression in patients with androgenetic alopecia by comparing balding and non-balding scalp at baseline, and to evaluate changes in JAK2 expression in balding scalp after 3 months of topical minoxidil 5% therapy. Clinical response will be assessed using standardized trichoscopic parameters.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Male adults aged 18 to 50 years with androgenetic alopecia. * Mild to moderate disease severity, defined as Hamilton-Norwood scale II to V. * Patients who are treatment-naive or willing to undergo an adequate washout period for prior hair loss therapies of at least 1 month. * Willing and able to provide written informed consent. Exclusion Criteria: * Other types of hair loss, including inflammatory or scarring alopecia. * Inflammatory scalp dermatoses, such as psoriasis or seborrheic dermatitis. * Use of systemic immunosuppressants, JAK inhibitors, or systemic corticosteroids within the last 12 months. * History of severe systemic disease, including renal, cardiovascular, or hepatic disease. * Chemotherapy during the last 5 years. * Bleeding disorders.
💊

What it tests

  • Topical Minoxidil 5% Solution
  • Scalp Punch Biopsy
  • Tissue JAK2 Protein Measurement by ELISA
📍

Where

1 site
Kasr El Aini Hospital
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy