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Effect of Lemon Juice and Apple Cider Vinegar on Postprandial Blood Glucose and Satiety in Healthy Individuals

RecruitingNAAges 18 Years - 35 YearsAllAlanya Alaaddin Keykubat University
NCT07563985 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical study aims to examine how acidic drinks (lemon juice and apple cider vinegar) affect blood sugar when consumed with a starchy food. The study focuses on healthy individuals and aims to understand whether these drinks can slow the rise in blood sugar after meals and affect feelings of fullness. The main questions this study aims to answer are: Do lemon juice or apple cider vinegar lower the rise in blood sugar after a meal? Do these drinks increase feelings of fullness? Do different amounts change their effects? Researchers will compare lemon juice and apple cider vinegar to see which one is more effective. Participants will: Consume white bread in the morning on an empty stomach with one of the following drinks: Water only Water with lemon juice (50 g or 100 g) Water with apple cider vinegar (10 g or 20 g) Have a one-week break between each test. Have their blood suga

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy male and female volunteers aged 18-35 years * Body Mass Index (BMI) between 18.5 and 25.0 kg/m² * Willingness to provide written informed consent * Ability to comply with study procedures and fasting requirements * No history of chronic metabolic, gastrointestinal, or endocrine diseases Exclusion Criteria: * Presence of any chronic disease (e.g., diabetes mellitus, cardiovascular disease, gastrointestinal disorders) * Food allergies or intolerances to study foods (white bread, lemon juice, apple cider vinegar) * BMI \<18.5 or \>25.0 kg/m² * Regular participation in high-intensity physical activity (≥5 days/week) * Current or recent (past 3 months) smoking or smoking cessation * Use of any medication or supplements affecting glucose metabolism * History of eating disorders * Pregnancy, lactation, or menopause * Female participants currently in menstruation period (testing will be postponed during menstruation days) * Alcohol consumption within 24 hours prior to testing days * Caffeine intake or major dietary changes on the day before testing
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What it tests

  • Control (Water + White Bread)
  • Lemon Juice 50 g
  • Lemon Juice 100 g
  • Apple Cider Vinegar 10 g
  • Apple Cider Vinegar 20 g
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Where

1 site
Alanya Alaaddin Keykubat University
Alanya, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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