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โ† Trials
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Impact of Novel vs. Usual Brand Menthol Cigarettes on Abuse Liability

RecruitingNAAges 21 Years - anyAllOhio State University Comprehensive Cancer Center
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In plain words

What the trial is, and whether it could suit you

This randomized, double-blind, crossover human laboratory study compares the abuse liability of cigarettes containing menthol and non-menthol cigarette variants, using the participant's usual brand menthol cigarette as a within-subject reference. Participants complete standardized laboratory smoking sessions, behavioral economic tasks, and a naturalistic observational period. The study examines differences in nicotine delivery, smoking behavior, and subjective effects across cigarette types in laboratory and real-world contexts.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Aged 21 years or older * Currently smoke cigarettes daily (โ‰ฅ 5 cigarettes/day) for at least the past 6 months, and their usual brand is menthol cigarettes * Willing to provide informed consent * Willing to abstain from all nicotine, tobacco, and smoked cannabis products for approximately 12 hours prior to each study visit * Own and regularly use a functional smartphone compatible with study procedures (e.g., completing daily assessments) * Willing to complete two weeks of daily assessments involving use of their usual brand menthol cigarettes and the study product * Able to read, speak, and understand English Exclusion Criteria: * Current diagnosis of any significant lung diseases (e.g., asthma, chronic obstructive pulmonary disease, cystic fibrosis) * History of a cardiac event or episode of cardiac distress (e.g., heart attack, hospitalization for chest pain) within the past 3 months * Currently pregnant, planning to become pregnant during the study period, or currently breastfeeding * Self-reported use of any non-cigarette nicotine or tobacco product (e.g., e-cigarettes, cigars, oral nicotine products) or cannabis on more than 10 days in the past 30 days * Self-reported current participation in a smoking cessation program or intention to quit smoking in the next 3 months * Self-reported difficulty with blood draws
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What it tests

  • Biospecimen Collection
  • Questionnaire Administration
  • Cigarette Purchase Task
  • Cross-Price Elasticity Task
  • Daily Diary Surveys
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Where

1 site
Ohio State University Comprehensive Cancer Center
Columbus, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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