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HoLEP-ThuLEP - Comparing Lasers for BPH Surgery

RecruitingNAAges 18 Years - anyMaleLudwig-Maximilians - University of Munich
NCT07565961 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult. Typical symptoms include a weak urinary stream, frequent urination, getting up at night to urinate, and a feeling that the bladder is not fully empty. When medication is no longer sufficient, surgical removal of the inner part of the prostate ("enucleation") is the recommended treatment. Two modern laser techniques are used for this operation. Holmium Laser Enucleation of the Prostate (HoLEP) is currently considered the reference standard, with very good long-term results and a low rate of re-operations. Thulium Laser Enucleation of the Prostate (ThuLEP) using a pulsed thulium laser is a newer alternative. Because the laser energy is delivered in short pulses, ThuLEP may allow more precise tissue cutting and better control of ble

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male, age ≥ 18 years * Clinically relevant benign prostatic syndrome (BPS) with an established indication for surgical treatment * International Prostate Symptom Score (IPSS) ≥ 8 * Prostate volume \> 40 ml * Signed written informed consent Exclusion Criteria: * Proven or suspected prostate cancer * Previous surgery of the prostate or urethra * Neurogenic bladder dysfunction * Anticoagulation therapy that cannot be paused perioperatively
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What it tests

  • Thulium Laser Enucleation of the Prostate (ThuLEP)
  • Holmium Laser Enucleation of the Prostate (HoLEP)
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Where

1 site
Urologische Klinik und Poliklinik, LMU Klinikum
Munich, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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