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โ† Trials
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Stress and Menstrual Health

RecruitingNAAges 22 Years - 38 YearsFemaleDuke University
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In plain words

What the trial is, and whether it could suit you

The goal of this experimental study is to determine how stressors that do not directly impact energy state or energy demands (hereafter called "non-energetic stressors") affect reproductive health in pre-menopausal women. It aims to do this by answering the following main questions: Do non-energetic stressors create a stress response? How does the stress response impact sex hormone concentration and thus menstrual dysfunction? If stress caused by non-energetic stressors does impact sex hormone concentration, does it do so primarily at the level of the brain or the level of the ovary? Participants will be enrolled in this study for 6 months. For two of these months, they will undergo a short stress intervention and provide samples to measure hormone concentration and total energy expenditure.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adult pre-menopausal females, 22-38 years old with a BMI of 18.5-30.0 * Habitually sedentary (less than 60 minutes MVPA/week) for Exercise cohort Exclusion Criteria: * Individuals on hormonal birth control (oral contraception, injection, implant, or intrauterine device) * Individuals with incidence in the last 6 months of childbirth, lactation, pregnancy, or functional hypothalamic amenorrhea (FHA) * Individuals with a BMI \<18.5 or \>30.0 * Individuals with reproductive disorders (e.g. endometriosis, polycystic ovarian syndrome (PCOS)) * Individuals taking thyroid medications * Individuals who have undergone or are undergoing menopause * MVPA \>60 min/week (for Exercise cohort)
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What it tests

  • Heat stress
  • Sleep stress
  • Exercise stress
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Where

1 site
Duke University
Durham, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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