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Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy

RecruitingNAAges 40 Years - 80 YearsAllUppsala University
NCT07569549 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis. The main questions it aims to answer are: Does surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery? What is the long-term risk of complications for both methods? Which method is more cost-effective for the healthcare system? Researchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient. Participants will: Be randomized to undergo either an operation with total joint arthroplasty or a trapezectomy. Undergo an initial evaluation and a health economic

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 40-80 years at inclusion * CMC-joint osteoarthritis grade 1-3 (Eaton-Littler classification) * Rest pain or pain reducing hand function with indication for surgery * Insufficient relief from non-operative treatment for ≥3 months (orthosis, OTC analgesics, cortisone injection) * Eligible for both prosthesis and trapezectomy per including surgeon * Non-smoker or complete smoking cessation ≥6 weeks prior to surgery Exclusion Criteria: * Previous surgery to thumb base or STT-joint * Ongoing general chronic pain condition or other pain in the same hand predominant over the thumb base pain. * Dementia or cognitive impairment * Trapezium height \<7 mm on plain radiograph * Active smoker * Osteoarthritis grade 4 (Eaton-Littler)
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What it tests

  • Implantation of trapeziometacarpal prosthesis
  • Trapeziectomy with Capsuloplasty
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Where

1 site
Department of Handsurgery, Uppsala University Hospital
Uppsala, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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