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IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT

Recruitingn/aAges 18 Years - 65 YearsAllSindh Institute of Urology and Transplantation
NCT07570771 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation. Our prospective observational study is designed to investigate how dialysis duration and residual urine output (diuresis) influence bladder capacity and compliance in ESRD patients who are waiting for kidney transplantation. The adult patients undergoing regular dialysis will be assessed clinically, and they will also be subjected to laboratory tests, imaging, and urodynamic studies. Through this study, we aim to determine the frequency of bladder malfunction and its correlation with the length of dialysis and the amount of urine excretion. The results might enhance the pre-

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD) * Patients on maintenance dialysis for a duration of 6 to 24 months * ESRD secondary to non-urological causes * Patients awaiting renal transplantation Exclusion Criteria: * Patients with diabetes mellitus * Patients with neurogenic bladder * Patients with prior urological surgeries * Patients with active urinary tract infection * Patients with pre-existing lower urinary tract symptoms before dialysis * Patients on medications affecting lower urinary tract function * Patients with neurological or systemic diseases affecting bladder function
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What it tests

  • Observational Assessment
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Where

1 site
Sindh Institute of Urology and Transplantation (SIUT)
Karachi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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