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Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.

RecruitingNAAges 18 Years - anyAllUniversity of Sao Paulo General Hospital
NCT07577700 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which old blood clots block the blood vessels in the lungs, making it harder for the heart to pump blood through the lungs. Surgery called pulmonary thromboendarterectomy can remove these clots and improve blood flow, but doctors need reliable ways to evaluate lung blood flow before and after surgery. This study will evaluate a bedside imaging method called electrical impedance tomography (EIT), which can measure how blood flows through different regions of the lungs without radiation or invasive procedures. Patients undergoing surgery for CTEPH will be monitored with EIT before and after surgery, and the results will be compared with standard lung perfusion imaging. The goal of this study is to determine whether EIT can provide useful information about lung blood flow and changes after surgery, and whether it coul

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📋 Eligibility rules (as published)
Inclusion Criteria: \- Patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) followed at the Pulmonology Service of InCor-HCFMUSP and scheduled for pulmonary thromboendarterectomy at InCor-FMUSP. Exclusion Criteria: * Age under 18 years * Pregnancy * Structural heart disease (atrial septal defect, ventricular septal defect, or valvular heart disease) * Cardiac arrhythmias * Use of a cardiac pacemaker or other implantable electronic device * Skin lesions on the thoracic region at the site of EIT electrode belt placement * Absence of central venous access on the day of the preoperative protocol evaluation * Difficulty understanding the procedures to be performed * Refusal to participate in the study (non-signing of the Informed Consent Form) * Refusal by the attending medical team
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What it tests

  • Electrical Impedance Tomography (EIT).
  • Pulmonary Perfusion SPECT-CT.
  • Pulmonary Thromboendarterectomy.
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Where

1 site
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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