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Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study

RecruitingNAAges 18 Years - anyFemaleUniversity of California, Los Angeles
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine if the addition of digital sensing data collected from phones and watches during the early stages of perinatal depression (PND) treatment can better predict treatment outcomes than using self-reported symptoms alone.STAND for PND: The UCLA Depression Grand Challenge (DGC) has previously developed a technology-assisted, scalable therapy system called STAND (Screening and Treatment for ANxiety and Depression) for perinatal depression (PND) and has demonstrated in an initial randomized clinical trial that this treatment intervention to be as effective as psychiatrist delivered care for PND. In this study, the investigators will administer STAND for PND for up to 12 weeks as part of study participation. There will be no comparison between our treatment intervention and a treatment as usual condition, as this is not a trial of efficacy. In the STAND f

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * At least 18 years of age * Able to read and communicate in English * Between 28 weeks pregnant and 12 weeks postpartum * Moderate-to-severe depression, as defined by Edinburgh Postnatal Depression Scale (EPDS) score โ‰ฅ11 * Not currently seeing a provider for mental health care * Own functioning iOS smartphone (iPhone 11 or newer, iOS 18 or newer) with access to reliable data plan and Wifi) * Able to read and understand a written informed consent form * Willingness to participate in treatment through the study and follow all study procedures, including providing HIPAA Authorization for research, installing a study app on personal iPhone, and wearing the provided Apple Watch for at least 20 hours every day in the first four weeks of the study (including while sleeping) Exclusion Criteria: * Currently receiving treatment by a therapist or a psychiatrist * Unstable suicidality (e.g., 2 or more suicide attempts or self-injurious behaviors resulting in hospitalization in the last 6 months) * Current substance use disorder that interferes with treatment: specifically, patients meeting diagnostic criteria for Substance Use Disorder (SUD) will be eligible for inclusion only if they are able to attend sessions while not under the influence of that substance, with the exception of individuals abusing opiates or freebase cocaine, who will be excluded * Principal diagnosis of psychosis unrelated to depression (unipolar or bipolar) * Neurological conditions * Severe uncontrolled medical conditions (e.g., anorexia nervosa, cardiac conditions requiring continuous monitoring) * Cognitive impairment (e.g., developmental disability, dementia) * Previously participated in the UCLA Depression Grand Challenge "New Moms Mood Tracking \& Wellbeing Study" (IRB #20-001924)
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What it tests

  • Perinatal depression online cognitive-behavioral therapy course
  • Clinical care (psychotherapy sessions)
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Where

1 site
University of California, Los Angeles
Los Angeles, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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