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Effect of Dairy Protein Yogourt vs Plant-based Yogourt on Body Weight, Body Composition, Bone Health and Gut Microbiota

RecruitingNAAges 40 Years - anyFemaleLaval University
NCT07578103 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The consumption of an adequate quantity of protein in the diet is essential to maintain a healthy body composition and functioning. It is also well established that all proteins are not equal regarding their ability to promote health benefits. Recently, we have innovated in that matter by showing that under the context of high intake of dietary fat, the dairy protein casein was more effective than a mix of proteins representative of a western diet to prevent body weight gain and insulin resistance. This was explained in part by modifications of the gut microbiota. This finding represents the main conceptual basis of the present research program that is aimed to determine the impact of dairy protein from yogurt compared to a plant-based equivalent on body composition indicators including muscle mass and bone mineral density, in relation to the profile of the gut microbiota, the production

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📋 Eligibility rules (as published)
Inclusion Criteria: * Postmenopausal women (absence of menstruation for at least 1 year and FSH \> 40 IU/L) * BMI between 27.0 and 39.9 kg/m² * Sedentary or moderately active Exclusion Criteria: * Body weight change greater than 5 kg in the 3 months preceding the study * Currently dieting or following specific dietary patterns * Previous or planned bariatric surgery * Food allergies or intolerances (particularly dairy proteins and lactose) * Serious or problematic health conditions (e.g., renal insufficiency, diabetes, Cushing's disease, Paget's disease, parathyroid disorders, inflammatory bowel disease, uncontrolled thyroid disease, etc.) * Fracture within the past year * Hormone therapy * Medications affecting bone metabolism (e.g., osteoporosis treatments, anti-estrogen therapy for breast cancer, epilepsy treatments) * Antibiotic use within the 6 months preceding the study * Use of probiotic supplements (capsules) * More than two alcoholic drinks per day * Smoking * Drug abuse
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What it tests

  • Dairy yogurt
  • Plant based yogurt
  • No yogurt
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Where

1 site
INAF, Université Laval
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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